GRR

GR Species Comparison & Mutation Data Base

NRR

S. Stoney Simons, Jr. & Mark Danielsen

Scientific Content

This data base is based on the published data base (Simons, Vitamins and Hormones, 49, 49-130 [1994]) with additions to make it as current as possible. However, there may be omissions and errors. The ultimate objective is to make this data base as complete and error-free as possible.

Therefore, your comments and/or corrections are greatly desired and should be sent to S. Stoney Simons. Comments on the organization of the database and ideas for improvement are welcome and should be sent to Mark Danielsen.

S. Stoney Simons, Jr.
Bldg. 8, Room B2A-07
NIDDK, NIH
8 Center Dr. MSC 0805
Bethesda, MD 20892-0805

Phone: 301-496-6796
FAX: 301-402-3572
email: steroids@helix.nih.gov

Mark Danielsen
Department of Biochemistry & Molecular Biology
Georgetown University School of Medicine
3900 Reservoir Rd. NW
Washington, DC 20007

Phone: (202) 687 4169
FAX: (202) 687 7186
email: dan@bc.georgetown.edu

Instructions

Links in the sequence comparison bring up the relevant information in the "Notes" frame.

Amino acid links in the "Notes" frame position the sequence comparison so that that amino acids can be seen.

Reference links in the "Notes" frame show the references for that amino acid in the frame below.

In the reference section, reference links displays abstracts of the paper in a separate browser window; notes for that amino acid can be displayed in the notes section

Comments on the organization of the database and ideas for improvement are welcome.

Abbreviations

The following abbreviations are used in the top frame of "Annotated Sequence Comparison and Mutational Analysis" to identify the species from which the GR was cloned:

r (rat)
m (mouse)
h (human)
p (primate, specifically tamarin)
g (guinea pig)
x (frog, specifically Xenopus).

In the second frame ("Notes"), the left hand column gives the position number and amino acid in the rat receptor. The right hand column gives the information from the literature about mutations at this position, with the species of the receptor in which the mutation was characterized identified by a capital letter using the same code as in the top frame.


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