Overview
The Nuclear Receptor Resource (NRR) Project is a collection of individual databases on members of the steroid and thyroid hormone receptor superfamily. Although the databases are located on different servers and are managed individually, they each form a node of the NRR. The NRR itself integrates the separate databases and allows an interactive forum for the dissemination of information about the superfamily.
For a general overview of nuclear receptors, the drug industry and the NRR see Jeanne McAdara's article in The Scientist.
Databases & Tools - Dynamic menu for researching databases and tools relevant to nuclear receptor research
Investigators - Look-up and/or add your self to the list of nuclear receptor investigators
Journals Online - List of journals relevant to nuclear receptors. Site hosted by UC Berkeley.
Research Funding - Link to the National Institute of Diabetes & Digestive & Kidney Disorders funding opportunities
Meetings - Links to web sites and organizations hosting conferences in the area of nuclear receptor research
Employment - Job posting and search tool for nuclear receptor researchers
NRR Components
Androgen Receptor (AR) - Gene mutation database and information regarding androgen receptor-interacting proteins
Estrogen Receptor (ER) - Facts, sequence alignments, knock-out phenotypes, sources for research products, and links to useful databases
Glucocorticoid Receptor (GR) - Facts, information sources for clones and antibodies, maps/sequences of GR expression vectors, and phenotypes of mutations
Peroxisome Proliferator-Activated Receptor (PPAR) - cDNA sequences, protein alignments, PPREs, and sources of cDNAs and antibodies
Steroid Receptor Associated Proteins (SRAPR) - Information on a variety of proteins that are known to interact with inactivated steroid receptor complexes
Thyroid Receptor (TR) - Wide variety of TR information including general comments, essays and data
Vitamin D Receptor - Comprehensive resource dealing with the structure and function of the protein that mediates the gene-regulatory effects of the vitamin D hormone
Related NRR Links
Steroid Structures - Structures and activities of common steroids - chemical and structural models. Please send us your favorite ligand for display
Graphics Library - Model slides used in a Medical Endocrinology course. Please donate slides that others may find interesting
Purified Nuclear Receptor Proteins- Suppliers of purified proteins for research